null
SMILES: CCOc1cc(\C=C2/S\C(=N\c3ccc(Cl)c(c3)C(O)=O)N(C)C2=O)cc(Cl)c1O
InChI Key: InChIKey=FGKGEXXAYGBGKQ-WPCGGMMTSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50525783 (CHEMBL4542058) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas-Arlington Curated by ChEMBL | Assay Description Antagonist activity at human PPARgamma LBD expressed in yeast AH109 cells assessed as reduction in rosiglitazone-stimulated PPARgamma/CBP interaction... | Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115047 BindingDB Entry DOI: 10.7270/Q2Q52T2F | |||||||||||
More data for this Ligand-Target Pair |