BDBM50525956 CHEMBL4465513

SMILES: CCN1CCN(CC1)c1nc2cc(F)ccc2c(=O)n1-c1ccc(OC)cc1

InChI Key: InChIKey=LDVRRMDXKLICNV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50525956   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50525956 (CHEMBL4465513) Show SMILES CCN1CCN(CC1)c1nc2cc(F)ccc2c(=O)n1-c1ccc(OC)cc1 Show InChI InChI=1S/C21H23FN4O2/c1-3-24-10-12-25(13-11-24)21-23-19-14-15(22)4-9-18(19)20(27)26(21)16-5-7-17(28-2)8-6-16/h4-9,14H,3,10-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a
Asahi Kasei Medical Corporation Curated by ChEMBL					Assay Description Agonist activity at recombinant human TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level after 30 mins by Fura-2 AM/...				J Med Chem 62: 1468-1483 (2019) Article DOI: 10.1021/acs.jmedchem.8b01615
					More data for this Ligand-Target Pair