Found 2 hits for monomerid = 50526009 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50526009
![PNG](/data/jpeg/tenK5052/BindingDB_50526009.png) (CHEMBL4563197)Show SMILES COc1ccc2[nH]cc(C3CCCN(CCCCn4c(=O)c(-c5ccccc5Cl)c5ccccn5c4=O)C3)c2c1 |(22.43,-29.85,;21.41,-28.7,;19.9,-29.01,;19.41,-30.47,;17.9,-30.77,;16.89,-29.62,;15.35,-29.61,;14.89,-28.14,;16.15,-27.25,;16.16,-25.71,;17.5,-24.95,;17.51,-23.41,;16.18,-22.62,;14.86,-23.39,;13.53,-22.61,;12.19,-23.38,;10.86,-22.6,;9.52,-23.36,;8.19,-22.58,;8.2,-21.04,;9.54,-20.28,;6.87,-20.26,;6.87,-18.73,;5.54,-17.96,;5.54,-16.42,;6.88,-15.65,;8.22,-16.42,;8.21,-17.96,;9.54,-18.74,;5.54,-21.03,;4.21,-20.25,;2.88,-21.03,;2.88,-22.57,;4.21,-23.33,;5.53,-22.57,;6.85,-23.34,;6.84,-24.88,;14.84,-24.93,;17.38,-28.16,;18.88,-27.86,)| Show InChI InChI=1S/C32H33ClN4O3/c1-40-23-13-14-28-25(19-23)26(20-34-28)22-9-8-16-35(21-22)15-6-7-18-37-31(38)30(24-10-2-3-11-27(24)33)29-12-4-5-17-36(29)32(37)39/h2-5,10-14,17,19-20,22,34H,6-9,15-16,18,21H2,1H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 176 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Warsaw
Curated by ChEMBL
| Assay Description Displacement of [3H]-8-OH-DPAT from recombinant human 5HT1A receptor expressed in CHO cell membranes measured after 60 mins by microbeta scintillatio... |
Eur J Med Chem 166: 144-158 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.031 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50526009
![PNG](/data/jpeg/tenK5052/BindingDB_50526009.png) (CHEMBL4563197)Show SMILES COc1ccc2[nH]cc(C3CCCN(CCCCn4c(=O)c(-c5ccccc5Cl)c5ccccn5c4=O)C3)c2c1 |(22.43,-29.85,;21.41,-28.7,;19.9,-29.01,;19.41,-30.47,;17.9,-30.77,;16.89,-29.62,;15.35,-29.61,;14.89,-28.14,;16.15,-27.25,;16.16,-25.71,;17.5,-24.95,;17.51,-23.41,;16.18,-22.62,;14.86,-23.39,;13.53,-22.61,;12.19,-23.38,;10.86,-22.6,;9.52,-23.36,;8.19,-22.58,;8.2,-21.04,;9.54,-20.28,;6.87,-20.26,;6.87,-18.73,;5.54,-17.96,;5.54,-16.42,;6.88,-15.65,;8.22,-16.42,;8.21,-17.96,;9.54,-18.74,;5.54,-21.03,;4.21,-20.25,;2.88,-21.03,;2.88,-22.57,;4.21,-23.33,;5.53,-22.57,;6.85,-23.34,;6.84,-24.88,;14.84,-24.93,;17.38,-28.16,;18.88,-27.86,)| Show InChI InChI=1S/C32H33ClN4O3/c1-40-23-13-14-28-25(19-23)26(20-34-28)22-9-8-16-35(21-22)15-6-7-18-37-31(38)30(24-10-2-3-11-27(24)33)29-12-4-5-17-36(29)32(37)39/h2-5,10-14,17,19-20,22,34H,6-9,15-16,18,21H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 459 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Warsaw
Curated by ChEMBL
| Assay Description Displacement of [3H]-citalopram from SERT in rat cortex tissue measured after 60 mins by microbeta scintillation counting analysis |
Eur J Med Chem 166: 144-158 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.031 |
More data for this Ligand-Target Pair | |