BDBM50526197 CHEMBL4443596

SMILES: Cc1cc(NN)n2nc(SCc3ccc(F)cc3)nc2n1

InChI Key: InChIKey=XYMBCEFNMIXIOG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50526197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50526197 (CHEMBL4443596) Show SMILES Cc1cc(NN)n2nc(SCc3ccc(F)cc3)nc2n1 Show InChI InChI=1S/C13H13FN6S/c1-8-6-11(18-15)20-12(16-8)17-13(19-20)21-7-9-2-4-10(14)5-3-9/h2-6,18H,7,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Zhengzhou University Curated by ChEMBL					Assay Description Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assay				Eur J Med Chem 166: 432-444 (2019) Article DOI: 10.1016/j.ejmech.2019.01.075
					More data for this Ligand-Target Pair