BDBM50526395 CHEMBL4444430

SMILES: OC1(CCC1)C(=O)N1CCN(CC1)C(=O)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=VQNLEJUAAGSHBQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50526395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid synthase (Homo sapiens (Human))	BDBM50526395 (CHEMBL4444430) Show SMILES OC1(CCC1)C(=O)N1CCN(CC1)C(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C22H24N2O3/c25-20(19-9-7-18(8-10-19)17-5-2-1-3-6-17)23-13-15-24(16-14-23)21(26)22(27)11-4-12-22/h1-3,5-10,27H,4,11-16H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics Curated by ChEMBL					Assay Description Inhibition of full length recombinant human FASN using acetyl-CoA/malonyl-CoA as substrate preincubated for 60 mins followed by substrate addition an...				Bioorg Med Chem Lett 29: 1001-1006 (2019) Article DOI: 10.1016/j.bmcl.2019.02.012
					More data for this Ligand-Target Pair