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BDBM50526410 CHEMBL4558932

SMILES: Cc1cc2c(NC(=O)C#C)cccc2n1-c1nc2CCCCc2c(NCc2ccccc2)n1

InChI Key: InChIKey=RKCSJJATGAWCBK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50526410   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transitional endoplasmic reticulum ATPase


(Homo sapiens (Human))		BDBM50526410
PNG
(CHEMBL4558932)
Show SMILES Cc1cc2c(NC(=O)C#C)cccc2n1-c1nc2CCCCc2c(NCc2ccccc2)n1
Show InChI InChI=1S/C27H25N5O/c1-3-25(33)29-23-14-9-15-24-21(23)16-18(2)32(24)27-30-22-13-8-7-12-20(22)26(31-27)28-17-19-10-5-4-6-11-19/h1,4-6,9-11,14-16H,7-8,12-13,17H2,2H3,(H,29,33)(H,28,30,31)
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
 38n/an/an/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of His-tagged p97 (unknown origin) in presence of ATP and PNP by UV-transparent microplate assay

J Med Chem 62: 2814-2829 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00144
More data for this
Ligand-Target Pair