BDBM50526629 ISOSILYBIN A
SMILES: COc1cc(ccc1O)[C@H]1Oc2ccc(cc2O[C@@H]1CO)[C@H]1Oc2cc(O)cc(O)c2C(=O)[C@@H]1O
InChI Key: InChIKey=FDQAOULAVFHKBX-HKTJVKLFSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50526629 (ISOSILYBIN A) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Mixed type inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV... | Bioorg Med Chem 27: 2499-2507 (2019) Article DOI: 10.1016/j.bmc.2019.03.013 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50526629 (ISOSILYBIN A) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Inhibition of monophenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction ... | Bioorg Med Chem 27: 2499-2507 (2019) Article DOI: 10.1016/j.bmc.2019.03.013 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50526629 (ISOSILYBIN A) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Inhibition of diphenolase activity of mushroom tyrosinase assessed as inhibition constant for free enzyme-inhibitor complex by measuring reduction in... | Bioorg Med Chem 27: 2499-2507 (2019) Article DOI: 10.1016/j.bmc.2019.03.013 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50526629 (ISOSILYBIN A) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | 1.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Mixed type inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis s... | Bioorg Med Chem 27: 2499-2507 (2019) Article DOI: 10.1016/j.bmc.2019.03.013 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50526629 (ISOSILYBIN A) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.67E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Inhibition of diphenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-DOPA substrate by UV-Vis spectrophoto... | Bioorg Med Chem 27: 2499-2507 (2019) Article DOI: 10.1016/j.bmc.2019.03.013 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Agaricus bisporus (Common mushroom)) | BDBM50526629 (ISOSILYBIN A) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gyeongsang National University Curated by ChEMBL | Assay Description Inhibition of monophenolase activity of mushroom tyrosinase assessed as reduction in dopachrome formation using L-Tyrosine substrate by UV-Vis spectr... | Bioorg Med Chem 27: 2499-2507 (2019) Article DOI: 10.1016/j.bmc.2019.03.013 | |||||||||||
More data for this Ligand-Target Pair |