BDBM50526725 CHEMBL4450748::US10807974, Example 122::US10995088, Example 122

SMILES: CNc1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)-c1ccccc1

InChI Key: InChIKey=GWNNAXLBTUZVHG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50526725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526725 (CHEMBL4450748 | US10807974, Example 122 | US109950...) Show SMILES CNc1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)-c1ccccc1 Show InChI InChI=1S/C17H17N3O2S2/c1-19-14-7-13(12-5-3-2-4-6-12)8-15(9-14)24(21,22)17-11-20-16(10-18)23-17/h2-9,11,19H,10,18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	397	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate ...				J Med Chem 63: 2308-2324 (2020) Article DOI: 10.1021/acs.jmedchem.9b01112
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526725 (CHEMBL4450748 | US10807974, Example 122 | US109950...) Show SMILES CNc1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)-c1ccccc1 Show InChI InChI=1S/C17H17N3O2S2/c1-19-14-7-13(12-5-3-2-4-6-12)8-15(9-14)24(21,22)17-11-20-16(10-18)23-17/h2-9,11,19H,10,18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL US Patent					Assay Description 10. Incubate for 20 hrs at room temp on a plate shaker, protected from light.				US Patent US10995088 (2021)
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50526725 (CHEMBL4450748 | US10807974, Example 122 | US109950...) Show SMILES CNc1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)-c1ccccc1 Show InChI InChI=1S/C17H17N3O2S2/c1-19-14-7-13(12-5-3-2-4-6-12)8-15(9-14)24(21,22)17-11-20-16(10-18)23-17/h2-9,11,19H,10,18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description LOXL2 batch is obtained from R&D systems/Bio-techne. Incubate for 20 hours at room temp on a plate shaker.				US Patent US10807974 (2020)
					More data for this Ligand-Target Pair