BDBM50526809 CHEMBL4465087

SMILES: Cc1c(Cc2nsc(=O)o2)c(=O)oc2cc3occ(-c4ccccc4)c3cc12

InChI Key: InChIKey=HCCIFUFGGXYTCH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50526809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
26S proteosome (Homo sapiens (Human))	BDBM50526809 (CHEMBL4465087) Show SMILES Cc1c(Cc2nsc(=O)o2)c(=O)oc2cc3occ(-c4ccccc4)c3cc12 Show InChI InChI=1S/C21H13NO5S/c1-11-13-7-15-16(12-5-3-2-4-6-12)10-25-17(15)9-18(13)26-20(23)14(11)8-19-22-28-21(24)27-19/h2-7,9-10H,8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Hangzhou Xixi Hospital Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome beta 5i				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111646
					More data for this Ligand-Target Pair