BDBM50526814 CHEMBL4473920

SMILES: C[C@@H](CC(=O)NCc1cccc2ccccc12)NC(=O)[C@H](CC(=O)NC(C)(C)C)NC(=O)CCc1ccccc1

InChI Key: InChIKey=NILMOKKCRYNYKK-CUNXSJBXSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-1/beta type-5 (Homo sapiens (Human))	BDBM50526814 (CHEMBL4473920) Show SMILES C[C@@H](CC(=O)NCc1cccc2ccccc12)NC(=O)[C@H](CC(=O)NC(C)(C)C)NC(=O)CCc1ccccc1 |r| Show InChI InChI=1S/C32H40N4O4/c1-22(19-29(38)33-21-25-15-10-14-24-13-8-9-16-26(24)25)34-31(40)27(20-30(39)36-32(2,3)4)35-28(37)18-17-23-11-6-5-7-12-23/h5-16,22,27H,17-21H2,1-4H3,(H,33,38)(H,34,40)(H,35,37)(H,36,39)/t22-,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hangzhou Xixi Hospital Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta 5c (unknown origin) after 1 hr by cell based assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111646
					More data for this Ligand-Target Pair
26S proteosome (Homo sapiens (Human))	BDBM50526814 (CHEMBL4473920) Show SMILES C[C@@H](CC(=O)NCc1cccc2ccccc12)NC(=O)[C@H](CC(=O)NC(C)(C)C)NC(=O)CCc1ccccc1 |r| Show InChI InChI=1S/C32H40N4O4/c1-22(19-29(38)33-21-25-15-10-14-24-13-8-9-16-26(24)25)34-31(40)27(20-30(39)36-32(2,3)4)35-28(37)18-17-23-11-6-5-7-12-23/h5-16,22,27H,17-21H2,1-4H3,(H,33,38)(H,34,40)(H,35,37)(H,36,39)/t22-,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Hangzhou Xixi Hospital Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta 5i (unknown origin) after 1 hr by cell based assay				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111646
					More data for this Ligand-Target Pair