BDBM50526819 CHEMBL4584763

SMILES: Clc1ccc(C(=O)Cn2ccnc2)c(Cl)c1Cl

InChI Key: InChIKey=GBJGCFUUYUYALL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526819   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heme oxygenase 1 (Rattus norvegicus (rat))	BDBM50526819 (CHEMBL4584763) Show SMILES Clc1ccc(C(=O)Cn2ccnc2)c(Cl)c1Cl Show InChI InChI=1S/C11H7Cl3N2O/c12-8-2-1-7(10(13)11(8)14)9(17)5-16-4-3-15-6-16/h1-4,6H,5H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat spleen microsome HO-1 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chr...				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111703
					More data for this Ligand-Target Pair
Heme oxygenase 2 (Rattus norvegicus (rat))	BDBM50526819 (CHEMBL4584763) Show SMILES Clc1ccc(C(=O)Cn2ccnc2)c(Cl)c1Cl Show InChI InChI=1S/C11H7Cl3N2O/c12-8-2-1-7(10(13)11(8)14)9(17)5-16-4-3-15-6-16/h1-4,6H,5H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat brain microsome HO-2 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chro...				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111703
					More data for this Ligand-Target Pair