BDBM50526824 CHEMBL4436773

SMILES: Brc1ccc(CC(=O)Cn2ccnn2)cc1

InChI Key: InChIKey=KGDFBUJUQIOHPF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50526824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heme oxygenase 1 (Rattus norvegicus (rat))	BDBM50526824 (CHEMBL4436773) Show SMILES Brc1ccc(CC(=O)Cn2ccnn2)cc1 Show InChI InChI=1S/C11H10BrN3O/c12-10-3-1-9(2-4-10)7-11(16)8-15-6-5-13-14-15/h1-6H,7-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat spleen microsome HO-1 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chr...				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111703
					More data for this Ligand-Target Pair
Heme oxygenase 2 (Rattus norvegicus (rat))	BDBM50526824 (CHEMBL4436773) Show SMILES Brc1ccc(CC(=O)Cn2ccnn2)cc1 Show InChI InChI=1S/C11H10BrN3O/c12-10-3-1-9(2-4-10)7-11(16)8-15-6-5-13-14-15/h1-6H,7-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat brain microsome HO-2 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chro...				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111703
					More data for this Ligand-Target Pair