BDBM50527375 CHEMBL4554392

SMILES: CCOCc1cc(C)c(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1

InChI Key: InChIKey=SMOWDHHBGOYEOK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50527375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT6A (Homo sapiens)	BDBM50527375 (CHEMBL4554392) Show SMILES CCOCc1cc(C)c(F)c(c1)C(=O)NNS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H19FN2O4S/c1-3-24-11-13-9-12(2)16(18)15(10-13)17(21)19-20-25(22,23)14-7-5-4-6-8-14/h4-10,20H,3,11H2,1-2H3,(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...				J Med Chem 63: 4655-4684 (2020) Article DOI: 10.1021/acs.jmedchem.9b02071
					More data for this Ligand-Target Pair