BDBM50527480 CHEMBL4446232

SMILES: CC1=C(C(C2=C(CCCC2=O)N1)c1cccc(c1)C(F)(F)F)C(=O)Nc1ccccc1C

InChI Key: InChIKey=HRGGIEKHJBVFBM-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527480   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 3 (Homo sapiens (Human))	BDBM50527480 (CHEMBL4446232) Show SMILES CC1=C(C(C2=C(CCCC2=O)N1)c1cccc(c1)C(F)(F)F)C(=O)Nc1ccccc1C |t:1,4| Show InChI InChI=1S/C25H23F3N2O2/c1-14-7-3-4-10-18(14)30-24(32)21-15(2)29-19-11-6-12-20(31)23(19)22(21)16-8-5-9-17(13-16)25(26,27)28/h3-5,7-10,13,22,29H,6,11-12H2,1-2H3,(H,30,32)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cell membrane assessed as stimulation of [35S]-GTPgammaS binding meas...				J Med Chem 63: 3577-3595 (2020) Article DOI: 10.1021/acs.jmedchem.9b02036
					More data for this Ligand-Target Pair
Free fatty acid receptor 3 (Homo sapiens (Human))	BDBM50527480 (CHEMBL4446232) Show SMILES CC1=C(C(C2=C(CCCC2=O)N1)c1cccc(c1)C(F)(F)F)C(=O)Nc1ccccc1C |t:1,4| Show InChI InChI=1S/C25H23F3N2O2/c1-14-7-3-4-10-18(14)30-24(32)21-15(2)29-19-11-6-12-20(31)23(19)22(21)16-8-5-9-17(13-16)25(26,27)28/h3-5,7-10,13,22,29H,6,11-12H2,1-2H3,(H,30,32)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...				J Med Chem 63: 3577-3595 (2020) Article DOI: 10.1021/acs.jmedchem.9b02036
					More data for this Ligand-Target Pair