BDBM50527504 CHEMBL4470372
SMILES: CC1=C(C(c2ccco2)C2=C(CCCC2=O)N1)C(=O)Nc1cccc(C)c1
InChI Key: InChIKey=LVGNCHBAIBJZCL-UHFFFAOYSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Free fatty acid receptor 3 (Homo sapiens (Human)) | BDBM50527504 (CHEMBL4470372) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind... | J Med Chem 63: 3577-3595 (2020) Article DOI: 10.1021/acs.jmedchem.9b02036 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 3 (Homo sapiens (Human)) | BDBM50527504 (CHEMBL4470372) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 4.57E+3 | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cell membrane assessed as stimulation of [35S]-GTPgammaS binding meas... | J Med Chem 63: 3577-3595 (2020) Article DOI: 10.1021/acs.jmedchem.9b02036 | |||||||||||
More data for this Ligand-Target Pair |