BDBM50528128 CHEMBL4514109

SMILES: Cc1ccccc1C(=O)CN1C(=O)NC(C)(C1=O)c1ccc(cc1)C#N

InChI Key: InChIKey=KESHNRSJKFDKAS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50528128   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Decaprenylphosphoryl-beta-D-ribose oxidase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50528128 (CHEMBL4514109) Show SMILES Cc1ccccc1C(=O)CN1C(=O)NC(C)(C1=O)c1ccc(cc1)C#N Show InChI InChI=1S/C20H17N3O3/c1-13-5-3-4-6-16(13)17(24)12-23-18(25)20(2,22-19(23)26)15-9-7-14(11-21)8-10-15/h3-10H,12H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis DprE1 expressed in Escherichia coli BL21(DE3) cells				J Med Chem 63: 5367-5386 (2020) Article DOI: 10.1021/acs.jmedchem.0c00107
					More data for this Ligand-Target Pair