BDBM50528217 CHEMBL4538188

SMILES: Brc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)S(=O)(=O)Nc1cccc2ccccc12

InChI Key: InChIKey=FTYKJNQUKYOMOL-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50528217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sirtuin-6 (SIRT6) (Homo sapiens (Human))	BDBM50528217 (CHEMBL4538188) Show SMILES Brc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)S(=O)(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C22H17BrN2O4S2/c23-17-8-12-19(13-9-17)30(26,27)24-18-10-14-20(15-11-18)31(28,29)25-22-7-3-5-16-4-1-2-6-21(16)22/h1-15,24-25H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.74E+5	n/a	n/a	n/a	n/a
Shanghai Jiao-Tong University School of Medicine Curated by ChEMBL					Assay Description Inhibition of SIRT6 (unknown origin)				J Med Chem 62: 6405-6421 (2019) Article DOI: 10.1021/acs.jmedchem.8b01749
					More data for this Ligand-Target Pair