BDBM50528256 CHEMBL4446656

SMILES: [#6]-[#8]-c1ccc(cc1-[#8])-[#6](=O)-[#6]-1=[#6]2-[#8]C([#6])([#6])[#6@@H](-[#6]\[#6]=[#6](\[#6])-[#6])-[#6][C@@]22[#6]-[#6@@H](-[#6]\[#6]=[#6](/[#6])-[#6])C([#6])([#6])[C@@]([#6]\[#6]=[#6](\[#6])-[#6])([#6]-1=O)[#6]2=O

InChI Key: InChIKey=GEMUMPJYCDKSDU-OAKZDBKWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIF1A/p300/CREB-binding protein (Homo sapiens (Human))	BDBM50528256 (CHEMBL4446656) Show SMILES [#6]-[#8]-c1ccc(cc1-[#8])-[#6](=O)-[#6]-1=[#6]2-[#8]C([#6])([#6])[#6@@H](-[#6]\[#6]=[#6](\[#6])-[#6])-[#6][C@@]22[#6]-[#6@@H](-[#6]\[#6]=[#6](/[#6])-[#6])C([#6])([#6])[C@@]([#6]\[#6]=[#6](\[#6])-[#6])([#6]-1=O)[#6]2=O |r,c:12,THB:27:26:43:11.41.12| Show InChI InChI=1S/C39H52O6/c1-23(2)12-15-27-21-38-22-28(16-13-24(3)4)37(9,10)45-34(38)31(32(41)26-14-17-30(44-11)29(40)20-26)33(42)39(35(38)43,36(27,7)8)19-18-25(5)6/h12-14,17-18,20,27-28,40H,15-16,19,21-22H2,1-11H3/t27-,28+,38+,39+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of P300 (unknown origin)				Eur J Med Chem 178: 259-286 (2019) Article DOI: 10.1016/j.ejmech.2019.05.078
					More data for this Ligand-Target Pair
HIF1A/p300/CREB-binding protein (Homo sapiens (Human))	BDBM50528256 (CHEMBL4446656) Show SMILES [#6]-[#8]-c1ccc(cc1-[#8])-[#6](=O)-[#6]-1=[#6]2-[#8]C([#6])([#6])[#6@@H](-[#6]\[#6]=[#6](\[#6])-[#6])-[#6][C@@]22[#6]-[#6@@H](-[#6]\[#6]=[#6](/[#6])-[#6])C([#6])([#6])[C@@]([#6]\[#6]=[#6](\[#6])-[#6])([#6]-1=O)[#6]2=O |r,c:12,THB:27:26:43:11.41.12| Show InChI InChI=1S/C39H52O6/c1-23(2)12-15-27-21-38-22-28(16-13-24(3)4)37(9,10)45-34(38)31(32(41)26-14-17-30(44-11)29(40)20-26)33(42)39(35(38)43,36(27,7)8)19-18-25(5)6/h12-14,17-18,20,27-28,40H,15-16,19,21-22H2,1-11H3/t27-,28+,38+,39+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of P300 (unknown origin) assessed as reduction in p53 acetylation				Eur J Med Chem 178: 259-286 (2019) Article DOI: 10.1016/j.ejmech.2019.05.078
					More data for this Ligand-Target Pair