BDBM50528337 CHEMBL4446709

SMILES: ONC(=O)C(NC(=O)c1ccc2[nH]ccc2c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1

InChI Key: InChIKey=WBTIPOZLPLCMOI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50528337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase (Homo sapiens (Human))	BDBM50528337 (CHEMBL4446709) Show SMILES ONC(=O)C(NC(=O)c1ccc2[nH]ccc2c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C23H16F3N3O3/c24-17-10-16(11-18(25)20(17)26)12-1-3-13(4-2-12)21(23(31)29-32)28-22(30)15-5-6-19-14(9-15)7-8-27-19/h1-11,21,27,32H,(H,28,30)(H,29,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757
					More data for this Ligand-Target Pair