BDBM50528350 CHEMBL4571223

SMILES: ONC(=O)C(NC(=O)c1cccc(F)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1

InChI Key: InChIKey=MGBKTOGBTWVMGA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50528350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase (Homo sapiens (Human))	BDBM50528350 (CHEMBL4571223) Show SMILES ONC(=O)C(NC(=O)c1cccc(F)c1)c1ccc(cc1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C21H14F4N2O3/c22-15-3-1-2-13(8-15)20(28)26-19(21(29)27-30)12-6-4-11(5-7-12)14-9-16(23)18(25)17(24)10-14/h1-10,19,30H,(H,26,28)(H,27,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	919	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of soluble human APN ectodomain stably expressed in HEK293 GnTI(-) cells using H-Leu-NHMec as substrate preincubated for 10 mins followed ...				J Med Chem 62: 7185-7209 (2019) Article DOI: 10.1021/acs.jmedchem.9b00757
					More data for this Ligand-Target Pair