BindingDB logo
myBDB logout

null

SMILES: COc1ccc(cc1F)-c1c[nH]nc1-c1cc(OC)c(OC)c(OC)c1

InChI Key: InChIKey=KZVVCHJZACSIRM-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50528633   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Similar to alpha-tubulin isoform 1


(Bos taurus)		BDBM50528633
PNG
(CHEMBL4522990)
Show SMILES COc1ccc(cc1F)-c1c[nH]nc1-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C19H19FN2O4/c1-23-15-6-5-11(7-14(15)20)13-10-21-22-18(13)12-8-16(24-2)19(26-4)17(9-12)25-3/h5-10H,1-4H3,(H,21,22)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Universit£ di Ferrara

Curated by ChEMBL


Assay Description
Inhibition of bovine brain tubulin assembly using GTP as substrate incubated for 20 mins by spectrophotometric method

Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111577
More data for this
Ligand-Target Pair