null

SMILES: CC(C(=O)NCc1ccc(cc1N1CCC(Cc2ccccc2)(CC1)N(C)C)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=PDAXSLZUMLDCAK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50528800   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50528800 (CHEMBL4586277) Show SMILES CC(C(=O)NCc1ccc(cc1N1CCC(Cc2ccccc2)(CC1)N(C)C)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C32H38F4N4O3S/c1-22(24-11-13-28(27(33)18-24)38-44(4,42)43)30(41)37-21-25-10-12-26(32(34,35)36)19-29(25)40-16-14-31(15-17-40,39(2)3)20-23-8-6-5-7-9-23/h5-13,18-19,22,38H,14-17,20-21H2,1-4H3,(H,37,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from recombinant human TRPV1 expressed in CHO cells incubated for 60 mins by liquid scintillation counter				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111634
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50528800 (CHEMBL4586277) Show SMILES CC(C(=O)NCc1ccc(cc1N1CCC(Cc2ccccc2)(CC1)N(C)C)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C32H38F4N4O3S/c1-22(24-11-13-28(27(33)18-24)38-44(4,42)43)30(41)37-21-25-10-12-26(32(34,35)36)19-29(25)40-16-14-31(15-17-40,39(2)3)20-23-8-6-5-7-9-23/h5-13,18-19,22,38H,14-17,20-21H2,1-4H3,(H,37,41)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	428	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO from full length human MOR expressed in chem5 cells incubated for 60 mins by liquid scintillation counter				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111634
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50528800 (CHEMBL4586277) Show SMILES CC(C(=O)NCc1ccc(cc1N1CCC(Cc2ccccc2)(CC1)N(C)C)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C32H38F4N4O3S/c1-22(24-11-13-28(27(33)18-24)38-44(4,42)43)30(41)37-21-25-10-12-26(32(34,35)36)19-29(25)40-16-14-31(15-17-40,39(2)3)20-23-8-6-5-7-9-23/h5-13,18-19,22,38H,14-17,20-21H2,1-4H3,(H,37,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8.20	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at recombinant human TRPV1 expressed in CHO cells assessed as as inhibition of capsaicin-induced calcium uptake incubated for 5 m...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111634
					More data for this Ligand-Target Pair