null

SMILES: CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)Nc1cccc2c1cc[nH]c2=O)C(F)(F)F

InChI Key: InChIKey=WNTFLRFKOYJRBM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50528801   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50528801 (CHEMBL4448866) Show SMILES CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)Nc1cccc2c1cc[nH]c2=O)C(F)(F)F Show InChI InChI=1S/C32H34F3N5O2/c1-39(2)31(20-22-7-4-3-5-8-22)14-17-40(18-15-31)28-19-24(32(33,34)35)12-11-23(28)21-37-30(42)38-27-10-6-9-26-25(27)13-16-36-29(26)41/h3-13,16,19H,14-15,17-18,20-21H2,1-2H3,(H,36,41)(H2,37,38,42)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO from full length human MOR expressed in chem5 cells incubated for 60 mins by liquid scintillation counter				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111634
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50528801 (CHEMBL4448866) Show SMILES CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)Nc1cccc2c1cc[nH]c2=O)C(F)(F)F Show InChI InChI=1S/C32H34F3N5O2/c1-39(2)31(20-22-7-4-3-5-8-22)14-17-40(18-15-31)28-19-24(32(33,34)35)12-11-23(28)21-37-30(42)38-27-10-6-9-26-25(27)13-16-36-29(26)41/h3-13,16,19H,14-15,17-18,20-21H2,1-2H3,(H,36,41)(H2,37,38,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from recombinant human TRPV1 expressed in CHO cells incubated for 60 mins by liquid scintillation counter				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111634
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50528801 (CHEMBL4448866) Show SMILES CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)Nc1cccc2c1cc[nH]c2=O)C(F)(F)F Show InChI InChI=1S/C32H34F3N5O2/c1-39(2)31(20-22-7-4-3-5-8-22)14-17-40(18-15-31)28-19-24(32(33,34)35)12-11-23(28)21-37-30(42)38-27-10-6-9-26-25(27)13-16-36-29(26)41/h3-13,16,19H,14-15,17-18,20-21H2,1-2H3,(H,36,41)(H2,37,38,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Agonist activity at recombinant human TRPV1 expressed in CHO cells assessed as increase in calcium uptake incubated for 5 mins in presence of 45Ca2+ ...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111634
					More data for this Ligand-Target Pair