null

SMILES: CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)Nc1ccc(CO)c(F)c1)C(F)(F)F

InChI Key: InChIKey=FUYXJJVZAWSEPB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50528805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50528805 (CHEMBL4555508) Show SMILES CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)Nc1ccc(CO)c(F)c1)C(F)(F)F Show InChI InChI=1S/C30H34F4N4O2/c1-37(2)29(18-21-6-4-3-5-7-21)12-14-38(15-13-29)27-16-24(30(32,33)34)10-8-22(27)19-35-28(40)36-25-11-9-23(20-39)26(31)17-25/h3-11,16-17,39H,12-15,18-20H2,1-2H3,(H2,35,36,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from recombinant human TRPV1 expressed in CHO cells incubated for 60 mins by liquid scintillation counter				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111634
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50528805 (CHEMBL4555508) Show SMILES CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)Nc1ccc(CO)c(F)c1)C(F)(F)F Show InChI InChI=1S/C30H34F4N4O2/c1-37(2)29(18-21-6-4-3-5-7-21)12-14-38(15-13-29)27-16-24(30(32,33)34)10-8-22(27)19-35-28(40)36-25-11-9-23(20-39)26(31)17-25/h3-11,16-17,39H,12-15,18-20H2,1-2H3,(H2,35,36,40)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]-DAMGO from full length human MOR expressed in chem5 cells incubated for 60 mins by liquid scintillation counter				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111634
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50528805 (CHEMBL4555508) Show SMILES CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)Nc1ccc(CO)c(F)c1)C(F)(F)F Show InChI InChI=1S/C30H34F4N4O2/c1-37(2)29(18-21-6-4-3-5-7-21)12-14-38(15-13-29)27-16-24(30(32,33)34)10-8-22(27)19-35-28(40)36-25-11-9-23(20-39)26(31)17-25/h3-11,16-17,39H,12-15,18-20H2,1-2H3,(H2,35,36,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	81	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at recombinant human TRPV1 expressed in CHO cells assessed as as inhibition of capsaicin-induced calcium uptake incubated for 5 m...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111634
					More data for this Ligand-Target Pair