BDBM50529248 CHEMBL4547122
SMILES: COc1ccc2cc(oc2c1)-c1nc(C(=O)NC(N)=N)c(N)nc1N
InChI Key: InChIKey=SRWPULZHZGLGIJ-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Urokinase-type plasminogen activator/surface receptor (Homo sapiens (Human)) | BDBM50529248![]() (CHEMBL4547122) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 439 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wollongong Curated by ChEMBL | Assay Description Inhibition of human kidney uPA using fluorogenic Z-Pyr-Gly-Arg-MCA as substrate measured after 15 mins by fluorometric analysis | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126753 | |||||||||||
More data for this Ligand-Target Pair |