BDBM50529256 CHEMBL4450426

SMILES: NC(=N)NC(=O)c1nc(c(N)nc1N)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=VTLAFUVKZLBWSY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator/surface receptor (Homo sapiens (Human))	BDBM50529256 (CHEMBL4450426) Show SMILES NC(=N)NC(=O)c1nc(c(N)nc1N)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H12F3N7O/c14-13(15,16)6-3-1-5(2-4-6)7-9(17)22-10(18)8(21-7)11(24)23-12(19)20/h1-4H,(H4,17,18,22)(H4,19,20,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of human kidney uPA using fluorogenic Z-Pyr-Gly-Arg-MCA as substrate measured after 15 mins by fluorometric analysis				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126753
					More data for this Ligand-Target Pair