BDBM50529385 CHEMBL4444112

SMILES: COc1c(cc(Cl)c(C)c1-c1ccc(cn1)C(=O)N(C)C)[C@H](C)Nc1ncnc(N)c1C#N

InChI Key: InChIKey=CPJFFEIKJCVXKN-ZDUSSCGKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50529385 (CHEMBL4444112) Show SMILES COc1c(cc(Cl)c(C)c1-c1ccc(cn1)C(=O)N(C)C)[C@H](C)Nc1ncnc(N)c1C#N |r| Show InChI InChI=1S/C23H24ClN7O2/c1-12-17(24)8-15(13(2)30-22-16(9-25)21(26)28-11-29-22)20(33-5)19(12)18-7-6-14(10-27-18)23(32)31(3)4/h6-8,10-11,13H,1-5H3,(H3,26,28,29,30)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) using D-myophosphatidylinositol 4,5-bisphosphate as substrate incubated for 120 mins by [gamma-33P]ATP based...				ACS Med Chem Lett 10: 1554-1560 (2019) Article DOI: 10.1021/acsmedchemlett.9b00334
					More data for this Ligand-Target Pair