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SMILES: CS(=O)(=O)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl

InChI Key: InChIKey=NTRCBEXHYIAYJI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529425   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Short transient receptor potential channel 5


(Homo sapiens (Human))		BDBM50529425
PNG
(CHEMBL4475647)
Show SMILES CS(=O)(=O)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl
Show InChI InChI=1S/C16H17ClN4O4S/c1-26(24,25)13-5-3-2-4-11(13)9-21-7-6-20(10-14(21)22)12-8-18-19-16(23)15(12)17/h2-5,8H,6-7,9-10H2,1H3,(H,19,23)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Goldfinch Bio Inc.

Curated by ChEMBL


Assay Description
Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...

ACS Med Chem Lett 10: 1579-1585 (2019)


Article DOI: 10.1021/acsmedchemlett.9b00430
BindingDB Entry DOI: 10.7270/Q2DN48HF
More data for this
Ligand-Target Pair