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BDBM50529429 CHEMBL4439131

SMILES: COc1c(cn[nH]c1=O)N1CCN(Cc2ccccc2C)C(=O)C1

InChI Key: InChIKey=PXYRNLDTLNMHFK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529429   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor protein 5 (TRPC5)


(Homo sapiens (Human))		BDBM50529429
PNG
(CHEMBL4439131)
Show SMILES COc1c(cn[nH]c1=O)N1CCN(Cc2ccccc2C)C(=O)C1
Show InChI InChI=1S/C17H20N4O3/c1-12-5-3-4-6-13(12)10-21-8-7-20(11-15(21)22)14-9-18-19-17(23)16(14)24-2/h3-6,9H,7-8,10-11H2,1-2H3,(H,19,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Goldfinch Bio Inc.

Curated by ChEMBL


Assay Description
Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...

ACS Med Chem Lett 10: 1579-1585 (2019)


Article DOI: 10.1021/acsmedchemlett.9b00430
More data for this
Ligand-Target Pair