BDBM50529441 CHEMBL4592027

SMILES: CC(N1CCN(CC1)c1cn[nH]c(=O)c1Br)c1ccccc1

InChI Key: InChIKey=RINUCCVFNORVNO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529441   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor protein 5 (TRPC5) (Homo sapiens (Human))	BDBM50529441 (CHEMBL4592027) Show SMILES CC(N1CCN(CC1)c1cn[nH]c(=O)c1Br)c1ccccc1 Show InChI InChI=1S/C16H19BrN4O/c1-12(13-5-3-2-4-6-13)20-7-9-21(10-8-20)14-11-18-19-16(22)15(14)17/h2-6,11-12H,7-10H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430
					More data for this Ligand-Target Pair