BDBM50529445 CHEMBL4471419

SMILES: Cc1ccccc1CN1CC2(C1)CCN(CC2)c1cn[nH]c(=O)c1Br

InChI Key: InChIKey=PXOOHBWWMRGDPC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529445   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor protein 5 (TRPC5) (Homo sapiens (Human))	BDBM50529445 (CHEMBL4471419) Show SMILES Cc1ccccc1CN1CC2(C1)CCN(CC2)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C19H23BrN4O/c1-14-4-2-3-5-15(14)11-23-12-19(13-23)6-8-24(9-7-19)16-10-21-22-18(25)17(16)20/h2-5,10H,6-9,11-13H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430
					More data for this Ligand-Target Pair