BDBM50529451 CHEMBL4469449

SMILES: Cc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1N1CCOCC1

InChI Key: InChIKey=RZKOYHYHOWFDPS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor protein 5 (TRPC5) (Homo sapiens (Human))	BDBM50529451 (CHEMBL4469449) Show SMILES Cc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1N1CCOCC1 Show InChI InChI=1S/C20H25N5O3/c1-15-4-2-3-5-16(15)13-25-7-6-24(14-18(25)26)17-12-21-22-20(27)19(17)23-8-10-28-11-9-23/h2-5,12H,6-11,13-14H2,1H3,(H,22,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430
					More data for this Ligand-Target Pair