BDBM50529453 CHEMBL4454641

SMILES: Cc1ccccc1CN1CC2(C1)CN(C2)c1cn[nH]c(=O)c1Br

InChI Key: InChIKey=FSOLWRXYFVHWJZ-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor protein 5 (TRPC5) (Homo sapiens (Human))	BDBM50529453 (CHEMBL4454641) Show SMILES Cc1ccccc1CN1CC2(C1)CN(C2)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C17H19BrN4O/c1-12-4-2-3-5-13(12)7-21-8-17(9-21)10-22(11-17)14-6-19-20-16(23)15(14)18/h2-6H,7-11H2,1H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430
					More data for this Ligand-Target Pair