BindingDB logo
myBDB logout

null

SMILES: Cc1cccnc1CN1CCN(CC1)c1cn[nH]c(=O)c1Cl

InChI Key: InChIKey=PFCRPZLPCGDRNZ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50529455   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Short transient receptor potential channel 5


(Homo sapiens (Human))		BDBM50529455
PNG
(CHEMBL4542897)
Show SMILES Cc1cccnc1CN1CCN(CC1)c1cn[nH]c(=O)c1Cl
Show InChI InChI=1S/C15H18ClN5O/c1-11-3-2-4-17-12(11)10-20-5-7-21(8-6-20)13-9-18-19-15(22)14(13)16/h2-4,9H,5-8,10H2,1H3,(H,19,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Goldfinch Bio Inc.

Curated by ChEMBL


Assay Description
Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...

ACS Med Chem Lett 10: 1579-1585 (2019)


Article DOI: 10.1021/acsmedchemlett.9b00430
BindingDB Entry DOI: 10.7270/Q2DN48HF
More data for this
Ligand-Target Pair