null

SMILES: CCC\C=C/C(=O)Nc1cc(Nc2nc(C)cc(n2)-c2cn(C)c3ccccc23)c(OC)cc1N(C)CCN(C)C

InChI Key: InChIKey=UZMIOFYGNLYZAY-GDNBJRDFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529688   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50529688 (CHEMBL4548960) Show SMILES CCC\C=C/C(=O)Nc1cc(Nc2nc(C)cc(n2)-c2cn(C)c3ccccc23)c(OC)cc1N(C)CCN(C)C Show InChI InChI=1S/C32H41N7O2/c1-8-9-10-15-31(40)34-26-19-27(30(41-7)20-29(26)38(5)17-16-37(3)4)36-32-33-22(2)18-25(35-32)24-21-39(6)28-14-12-11-13-23(24)28/h10-15,18-21H,8-9,16-17H2,1-7H3,(H,34,40)(H,33,35,36)/b15-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R double mutant (unknown origin) using substrate-biotin by ELISA-based mobility shift assay				Eur J Med Chem 163: 367-380 (2019) Article DOI: 10.1016/j.ejmech.2018.11.069
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50529688 (CHEMBL4548960) Show SMILES CCC\C=C/C(=O)Nc1cc(Nc2nc(C)cc(n2)-c2cn(C)c3ccccc23)c(OC)cc1N(C)CCN(C)C Show InChI InChI=1S/C32H41N7O2/c1-8-9-10-15-31(40)34-26-19-27(30(41-7)20-29(26)38(5)17-16-37(3)4)36-32-33-22(2)18-25(35-32)24-21-39(6)28-14-12-11-13-23(24)28/h10-15,18-21H,8-9,16-17H2,1-7H3,(H,34,40)(H,33,35,36)/b15-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of wild-type EGFR (unknown origin) using substrate-biotin by ELISA-based mobility shift assay				Eur J Med Chem 163: 367-380 (2019) Article DOI: 10.1016/j.ejmech.2018.11.069
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50529688 (CHEMBL4548960) Show SMILES CCC\C=C/C(=O)Nc1cc(Nc2nc(C)cc(n2)-c2cn(C)c3ccccc23)c(OC)cc1N(C)CCN(C)C Show InChI InChI=1S/C32H41N7O2/c1-8-9-10-15-31(40)34-26-19-27(30(41-7)20-29(26)38(5)17-16-37(3)4)36-32-33-22(2)18-25(35-32)24-21-39(6)28-14-12-11-13-23(24)28/h10-15,18-21H,8-9,16-17H2,1-7H3,(H,34,40)(H,33,35,36)/b15-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of wild-type EGFR (unknown origin) using substrate-biotin by ELISA-based mobility shift assay				Eur J Med Chem 163: 367-380 (2019) Article DOI: 10.1016/j.ejmech.2018.11.069
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50529688 (CHEMBL4548960) Show SMILES CCC\C=C/C(=O)Nc1cc(Nc2nc(C)cc(n2)-c2cn(C)c3ccccc23)c(OC)cc1N(C)CCN(C)C Show InChI InChI=1S/C32H41N7O2/c1-8-9-10-15-31(40)34-26-19-27(30(41-7)20-29(26)38(5)17-16-37(3)4)36-32-33-22(2)18-25(35-32)24-21-39(6)28-14-12-11-13-23(24)28/h10-15,18-21H,8-9,16-17H2,1-7H3,(H,34,40)(H,33,35,36)/b15-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R double mutant (unknown origin) using substrate-biotin by ELISA-based mobility shift assay				Eur J Med Chem 163: 367-380 (2019) Article DOI: 10.1016/j.ejmech.2018.11.069
					More data for this Ligand-Target Pair