null

SMILES: COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(C)cc(n1)-c1cn(C)c2ccccc12

InChI Key: InChIKey=MFMJUEMNPKCWHW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529689   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50529689 (CHEMBL4557005) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(C)cc(n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C29H35N7O2/c1-8-28(37)31-23-16-24(27(38-7)17-26(23)35(5)14-13-34(3)4)33-29-30-19(2)15-22(32-29)21-18-36(6)25-12-10-9-11-20(21)25/h8-12,15-18H,1,13-14H2,2-7H3,(H,31,37)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R double mutant (unknown origin) using substrate-biotin by ELISA-based mobility shift assay				Eur J Med Chem 163: 367-380 (2019) Article DOI: 10.1016/j.ejmech.2018.11.069
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50529689 (CHEMBL4557005) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(C)cc(n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C29H35N7O2/c1-8-28(37)31-23-16-24(27(38-7)17-26(23)35(5)14-13-34(3)4)33-29-30-19(2)15-22(32-29)21-18-36(6)25-12-10-9-11-20(21)25/h8-12,15-18H,1,13-14H2,2-7H3,(H,31,37)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of wild-type EGFR (unknown origin) using substrate-biotin by ELISA-based mobility shift assay				Eur J Med Chem 163: 367-380 (2019) Article DOI: 10.1016/j.ejmech.2018.11.069
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50529689 (CHEMBL4557005) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(C)cc(n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C29H35N7O2/c1-8-28(37)31-23-16-24(27(38-7)17-26(23)35(5)14-13-34(3)4)33-29-30-19(2)15-22(32-29)21-18-36(6)25-12-10-9-11-20(21)25/h8-12,15-18H,1,13-14H2,2-7H3,(H,31,37)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R double mutant (unknown origin) using substrate-biotin by ELISA-based mobility shift assay				Eur J Med Chem 163: 367-380 (2019) Article DOI: 10.1016/j.ejmech.2018.11.069
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50529689 (CHEMBL4557005) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nc(C)cc(n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C29H35N7O2/c1-8-28(37)31-23-16-24(27(38-7)17-26(23)35(5)14-13-34(3)4)33-29-30-19(2)15-22(32-29)21-18-36(6)25-12-10-9-11-20(21)25/h8-12,15-18H,1,13-14H2,2-7H3,(H,31,37)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of wild-type EGFR (unknown origin) using substrate-biotin by ELISA-based mobility shift assay				Eur J Med Chem 163: 367-380 (2019) Article DOI: 10.1016/j.ejmech.2018.11.069
					More data for this Ligand-Target Pair