null

SMILES: COc1cc(N(C)CCN(C)C)c(NC(=O)C(F)=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12

InChI Key: InChIKey=RZHOAFIHCFUPIH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529703   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50529703 (CHEMBL4557772) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C(F)=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C28H32FN7O2/c1-18(29)27(37)31-22-15-23(26(38-6)16-25(22)35(4)14-13-34(2)3)33-28-30-12-11-21(32-28)20-17-36(5)24-10-8-7-9-19(20)24/h7-12,15-17H,1,13-14H2,2-6H3,(H,31,37)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R double mutant (unknown origin) using substrate-biotin by ELISA-based mobility shift assay				Eur J Med Chem 163: 367-380 (2019) Article DOI: 10.1016/j.ejmech.2018.11.069
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50529703 (CHEMBL4557772) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C(F)=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C28H32FN7O2/c1-18(29)27(37)31-22-15-23(26(38-6)16-25(22)35(4)14-13-34(2)3)33-28-30-12-11-21(32-28)20-17-36(5)24-10-8-7-9-19(20)24/h7-12,15-17H,1,13-14H2,2-6H3,(H,31,37)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of wild-type EGFR (unknown origin) using substrate-biotin by ELISA-based mobility shift assay				Eur J Med Chem 163: 367-380 (2019) Article DOI: 10.1016/j.ejmech.2018.11.069
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50529703 (CHEMBL4557772) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C(F)=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C28H32FN7O2/c1-18(29)27(37)31-22-15-23(26(38-6)16-25(22)35(4)14-13-34(2)3)33-28-30-12-11-21(32-28)20-17-36(5)24-10-8-7-9-19(20)24/h7-12,15-17H,1,13-14H2,2-6H3,(H,31,37)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R double mutant (unknown origin) using substrate-biotin by ELISA-based mobility shift assay				Eur J Med Chem 163: 367-380 (2019) Article DOI: 10.1016/j.ejmech.2018.11.069
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50529703 (CHEMBL4557772) Show SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C(F)=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12 Show InChI InChI=1S/C28H32FN7O2/c1-18(29)27(37)31-22-15-23(26(38-6)16-25(22)35(4)14-13-34(2)3)33-28-30-12-11-21(32-28)20-17-36(5)24-10-8-7-9-19(20)24/h7-12,15-17H,1,13-14H2,2-6H3,(H,31,37)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science & Technology Normal University Curated by ChEMBL					Assay Description Inhibition of wild-type EGFR (unknown origin) using substrate-biotin by ELISA-based mobility shift assay				Eur J Med Chem 163: 367-380 (2019) Article DOI: 10.1016/j.ejmech.2018.11.069
					More data for this Ligand-Target Pair