null

SMILES: [#6]-c1cccc(n1)C#C\[#6]=[#6]-1/[#6]-[#6]-[#7](-[#6]-[#6]-1)S(=O)(=O)[#6]-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1

InChI Key: InChIKey=BKTNVFHODQILHH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529981   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50529981 (CHEMBL4474134) Show SMILES [#6]-c1cccc(n1)C#C\[#6]=[#6]-1/[#6]-[#6]-[#7](-[#6]-[#6]-1)S(=O)(=O)[#6]-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C21H28N2O2S/c1-18-7-5-11-21(22-18)12-6-10-19-13-15-23(16-14-19)26(24,25)17-20-8-3-2-4-9-20/h5,7,10-11,20H,2-4,8-9,13-17H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	456	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Recordati S.p.A. Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from human mGlu5 receptor expressed in CHO-TREx cell membranes after 60 mins by liquid scintillation spectrometric analysis				J Med Chem 62: 1246-1273 (2019) Article DOI: 10.1021/acs.jmedchem.8b01226
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50529981 (CHEMBL4474134) Show SMILES [#6]-c1cccc(n1)C#C\[#6]=[#6]-1/[#6]-[#6]-[#7](-[#6]-[#6]-1)S(=O)(=O)[#6]-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C21H28N2O2S/c1-18-7-5-11-21(22-18)12-6-10-19-13-15-23(16-14-19)26(24,25)17-20-8-3-2-4-9-20/h5,7,10-11,20H,2-4,8-9,13-17H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	456	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Recordati S.p.A. Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from human mGlu5 receptor expressed in CHO-TREx cell membranes after 60 mins by liquid scintillation spectrometric analysis				J Med Chem 62: 1246-1273 (2019) Article DOI: 10.1021/acs.jmedchem.8b01226
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50529981 (CHEMBL4474134) Show SMILES [#6]-c1cccc(n1)C#C\[#6]=[#6]-1/[#6]-[#6]-[#7](-[#6]-[#6]-1)S(=O)(=O)[#6]-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C21H28N2O2S/c1-18-7-5-11-21(22-18)12-6-10-19-13-15-23(16-14-19)26(24,25)17-20-8-3-2-4-9-20/h5,7,10-11,20H,2-4,8-9,13-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Recordati S.p.A. Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGlu1 receptor expressed in CHO-TREx cell membranes after 30 mins by liquid scintillation spectrometric analysis				J Med Chem 62: 1246-1273 (2019) Article DOI: 10.1021/acs.jmedchem.8b01226
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50529981 (CHEMBL4474134) Show SMILES [#6]-c1cccc(n1)C#C\[#6]=[#6]-1/[#6]-[#6]-[#7](-[#6]-[#6]-1)S(=O)(=O)[#6]-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1 Show InChI InChI=1S/C21H28N2O2S/c1-18-7-5-11-21(22-18)12-6-10-19-13-15-23(16-14-19)26(24,25)17-20-8-3-2-4-9-20/h5,7,10-11,20H,2-4,8-9,13-17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Recordati S.p.A. Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from rat mGlu1 receptor expressed in CHO-TREx cell membranes after 30 mins by liquid scintillation spectrometric analysis				J Med Chem 62: 1246-1273 (2019) Article DOI: 10.1021/acs.jmedchem.8b01226
					More data for this Ligand-Target Pair