BDBM50530316 CHEMBL4455046

SMILES: OC(=O)c1ccc(Nc2nc(cs2)-c2ccccn2)cc1

InChI Key: InChIKey=AHSIVPPUDXPGPA-UHFFFAOYSA-N

Data: 4 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50530316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50530316 (CHEMBL4455046) Show SMILES OC(=O)c1ccc(Nc2nc(cs2)-c2ccccn2)cc1 Show InChI InChI=1S/C15H11N3O2S/c19-14(20)10-4-6-11(7-5-10)17-15-18-13(9-21-15)12-3-1-2-8-16-12/h1-9H,(H,17,18)(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assay				J Med Chem 62: 1817-1836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01765
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50530316 (CHEMBL4455046) Show SMILES OC(=O)c1ccc(Nc2nc(cs2)-c2ccccn2)cc1 Show InChI InChI=1S/C15H11N3O2S/c19-14(20)10-4-6-11(7-5-10)17-15-18-13(9-21-15)12-3-1-2-8-16-12/h1-9H,(H,17,18)(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Binding affinity to recombinant human GST-tagged CK2alpha after 120 secs by surface plasmon resonance analysis				J Med Chem 62: 1817-1836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01765
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50530316 (CHEMBL4455046) Show SMILES OC(=O)c1ccc(Nc2nc(cs2)-c2ccccn2)cc1 Show InChI InChI=1S/C15H11N3O2S/c19-14(20)10-4-6-11(7-5-10)17-15-18-13(9-21-15)12-3-1-2-8-16-12/h1-9H,(H,17,18)(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assay				J Med Chem 62: 1803-1816 (2019) Article DOI: 10.1021/acs.jmedchem.8b01766
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50530316 (CHEMBL4455046) Show SMILES OC(=O)c1ccc(Nc2nc(cs2)-c2ccccn2)cc1 Show InChI InChI=1S/C15H11N3O2S/c19-14(20)10-4-6-11(7-5-10)17-15-18-13(9-21-15)12-3-1-2-8-16-12/h1-9H,(H,17,18)(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Binding affinity to recombinant human GST-tagged CK2alpha after 120 secs by surface plasmon resonance analysis				J Med Chem 62: 1817-1836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01765
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50530316 (CHEMBL4455046) Show SMILES OC(=O)c1ccc(Nc2nc(cs2)-c2ccccn2)cc1 Show InChI InChI=1S/C15H11N3O2S/c19-14(20)10-4-6-11(7-5-10)17-15-18-13(9-21-15)12-3-1-2-8-16-12/h1-9H,(H,17,18)(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assay				J Med Chem 62: 1803-1816 (2019) Article DOI: 10.1021/acs.jmedchem.8b01766
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50530316 (CHEMBL4455046) Show SMILES OC(=O)c1ccc(Nc2nc(cs2)-c2ccccn2)cc1 Show InChI InChI=1S/C15H11N3O2S/c19-14(20)10-4-6-11(7-5-10)17-15-18-13(9-21-15)12-3-1-2-8-16-12/h1-9H,(H,17,18)(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assay				J Med Chem 62: 1817-1836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01765
					More data for this Ligand-Target Pair