BDBM50530318 CHEMBL4526405

SMILES: COc1cccc(c1)-c1csc(Nc2ccc(cc2)C(O)=O)n1

InChI Key: InChIKey=NOMAILRWROGPEM-UHFFFAOYSA-N

Data: 4 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50530318   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50530318 (CHEMBL4526405) Show SMILES COc1cccc(c1)-c1csc(Nc2ccc(cc2)C(O)=O)n1 Show InChI InChI=1S/C17H14N2O3S/c1-22-14-4-2-3-12(9-14)15-10-23-17(19-15)18-13-7-5-11(6-8-13)16(20)21/h2-10H,1H3,(H,18,19)(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Binding affinity to recombinant human GST-tagged CK2alpha after 120 secs by surface plasmon resonance analysis				J Med Chem 62: 1817-1836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01765
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50530318 (CHEMBL4526405) Show SMILES COc1cccc(c1)-c1csc(Nc2ccc(cc2)C(O)=O)n1 Show InChI InChI=1S/C17H14N2O3S/c1-22-14-4-2-3-12(9-14)15-10-23-17(19-15)18-13-7-5-11(6-8-13)16(20)21/h2-10H,1H3,(H,18,19)(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Binding affinity to recombinant human GST-tagged CK2alpha after 120 secs by surface plasmon resonance analysis				J Med Chem 62: 1817-1836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01765
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50530318 (CHEMBL4526405) Show SMILES COc1cccc(c1)-c1csc(Nc2ccc(cc2)C(O)=O)n1 Show InChI InChI=1S/C17H14N2O3S/c1-22-14-4-2-3-12(9-14)15-10-23-17(19-15)18-13-7-5-11(6-8-13)16(20)21/h2-10H,1H3,(H,18,19)(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assay				J Med Chem 62: 1803-1816 (2019) Article DOI: 10.1021/acs.jmedchem.8b01766
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50530318 (CHEMBL4526405) Show SMILES COc1cccc(c1)-c1csc(Nc2ccc(cc2)C(O)=O)n1 Show InChI InChI=1S/C17H14N2O3S/c1-22-14-4-2-3-12(9-14)15-10-23-17(19-15)18-13-7-5-11(6-8-13)16(20)21/h2-10H,1H3,(H,18,19)(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assay				J Med Chem 62: 1817-1836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01765
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50530318 (CHEMBL4526405) Show SMILES COc1cccc(c1)-c1csc(Nc2ccc(cc2)C(O)=O)n1 Show InChI InChI=1S/C17H14N2O3S/c1-22-14-4-2-3-12(9-14)15-10-23-17(19-15)18-13-7-5-11(6-8-13)16(20)21/h2-10H,1H3,(H,18,19)(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assay				J Med Chem 62: 1803-1816 (2019) Article DOI: 10.1021/acs.jmedchem.8b01766
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50530318 (CHEMBL4526405) Show SMILES COc1cccc(c1)-c1csc(Nc2ccc(cc2)C(O)=O)n1 Show InChI InChI=1S/C17H14N2O3S/c1-22-14-4-2-3-12(9-14)15-10-23-17(19-15)18-13-7-5-11(6-8-13)16(20)21/h2-10H,1H3,(H,18,19)(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lyon Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged CK2alpha in presence of ATP by radiometric kinase assay				J Med Chem 62: 1817-1836 (2019) Article DOI: 10.1021/acs.jmedchem.8b01765
					More data for this Ligand-Target Pair