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BDBM50531480 CHEMBL4447524

SMILES: COc1ccc2n(CCCCCC(=O)NO)cc(C(=O)Nc3nc4ccccc4s3)c(=O)c2c1

InChI Key: InChIKey=UTTRAIILHMTWLY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50531480   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyamine deacetylase HDAC10


(Mus musculus)		BDBM50531480
PNG
(CHEMBL4447524)
Show SMILES COc1ccc2n(CCCCCC(=O)NO)cc(C(=O)Nc3nc4ccccc4s3)c(=O)c2c1
Show InChI InChI=1S/C24H24N4O5S/c1-33-15-10-11-19-16(13-15)22(30)17(14-28(19)12-6-2-3-9-21(29)27-32)23(31)26-24-25-18-7-4-5-8-20(18)34-24/h4-5,7-8,10-11,13-14,32H,2-3,6,9,12H2,1H3,(H,27,29)(H,25,26,31)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 28n/an/an/an/an/an/a



S£o Paulo State University (UNESP)

Curated by ChEMBL


Assay Description
Inhibition of mouse liver HDAC using Boc-Lys (Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins ...

Eur J Med Chem 164: 8-26 (2019)


Article DOI: 10.1016/j.ejmech.2018.12.033
More data for this
Ligand-Target Pair