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SMILES: Cc1nc(no1)-c1csc(c1)S(N)(=O)=O

InChI Key: InChIKey=WSYKOUVIKYOXFB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50531517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50531517 (CHEMBL4452965) Show SMILES Cc1nc(no1)-c1csc(c1)S(N)(=O)=O Show InChI InChI=1S/C7H7N3O3S2/c1-4-9-7(10-13-4)5-2-6(14-3-5)15(8,11)12/h2-3H,1H3,(H2,8,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Saint Petersburg State University Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 assessed as reduction in CO2 hydration after 15 mins by phenol red staining-based stopped flow assay				Eur J Med Chem 164: 92-105 (2019) Article DOI: 10.1016/j.ejmech.2018.12.049
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50531517 (CHEMBL4452965) Show SMILES Cc1nc(no1)-c1csc(c1)S(N)(=O)=O Show InChI InChI=1S/C7H7N3O3S2/c1-4-9-7(10-13-4)5-2-6(14-3-5)15(8,11)12/h2-3H,1H3,(H2,8,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Saint Petersburg State University Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 assessed as reduction in CO2 hydration after 15 mins by phenol red staining-based stopped flow assay				Eur J Med Chem 164: 92-105 (2019) Article DOI: 10.1016/j.ejmech.2018.12.049
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50531517 (CHEMBL4452965) Show SMILES Cc1nc(no1)-c1csc(c1)S(N)(=O)=O Show InChI InChI=1S/C7H7N3O3S2/c1-4-9-7(10-13-4)5-2-6(14-3-5)15(8,11)12/h2-3H,1H3,(H2,8,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Saint Petersburg State University Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 assessed as reduction in CO2 hydration after 15 mins by phenol red staining-based stopped flow assay				Eur J Med Chem 164: 92-105 (2019) Article DOI: 10.1016/j.ejmech.2018.12.049
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50531517 (CHEMBL4452965) Show SMILES Cc1nc(no1)-c1csc(c1)S(N)(=O)=O Show InChI InChI=1S/C7H7N3O3S2/c1-4-9-7(10-13-4)5-2-6(14-3-5)15(8,11)12/h2-3H,1H3,(H2,8,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Saint Petersburg State University Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 assessed as reduction in CO2 hydration after 15 mins by phenol red staining-based stopped flow assay				Eur J Med Chem 164: 92-105 (2019) Article DOI: 10.1016/j.ejmech.2018.12.049
					More data for this Ligand-Target Pair