BDBM50531978 CHEMBL4466342

SMILES: CCCCc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(F)c(O)c1

InChI Key: InChIKey=ZHQIHJFXLFNJRR-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50531978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human))	BDBM50531978 (CHEMBL4466342) Show SMILES CCCCc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(F)c(O)c1 Show InChI InChI=1S/C23H26FNO3/c1-2-3-4-16-5-7-17(8-6-16)22(27)18-11-13-25(14-12-18)23(28)19-9-10-20(24)21(26)15-19/h5-10,15,18,26H,2-4,11-14H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of human ABHD6 expressed in HEK293 cell homogenates pre-incubated for 30 mins in presence of [1,2,3-3H]2-OG by liquid scintillation spectr...				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50531978 (CHEMBL4466342) Show SMILES CCCCc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(F)c(O)c1 Show InChI InChI=1S/C23H26FNO3/c1-2-3-4-16-5-7-17(8-6-16)22(27)18-11-13-25(14-12-18)23(28)19-9-10-20(24)21(26)15-19/h5-10,15,18,26H,2-4,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of FAAH in human U937 cell homogenates using [ethanolamine-1-3H]AEA as substrate after 15 mins by liquid scintillation spectroscopy				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50531978 (CHEMBL4466342) Show SMILES CCCCc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(F)c(O)c1 Show InChI InChI=1S/C23H26FNO3/c1-2-3-4-16-5-7-17(8-6-16)22(27)18-11-13-25(14-12-18)23(28)19-9-10-20(24)21(26)15-19/h5-10,15,18,26H,2-4,11-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	262	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MAGL using 4-NPA as substrate after 30 mins				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50531978 (CHEMBL4466342) Show SMILES CCCCc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(F)c(O)c1 Show InChI InChI=1S/C23H26FNO3/c1-2-3-4-16-5-7-17(8-6-16)22(27)18-11-13-25(14-12-18)23(28)19-9-10-20(24)21(26)15-19/h5-10,15,18,26H,2-4,11-14H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 to human CB1 receptor expressed in cell membranes after 90 mins by liquid scintillation counting				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483
					More data for this Ligand-Target Pair
Monoacylglycerol lipase ABHD12 (Homo sapiens (Human))	BDBM50531978 (CHEMBL4466342) Show SMILES CCCCc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(F)c(O)c1 Show InChI InChI=1S/C23H26FNO3/c1-2-3-4-16-5-7-17(8-6-16)22(27)18-11-13-25(14-12-18)23(28)19-9-10-20(24)21(26)15-19/h5-10,15,18,26H,2-4,11-14H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of human ABHD12 expressed in HEK293 cell homogenates pre-incubated for 30 mins in presence of [1,2,3-3H]2-OG by liquid scintillation spect...				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50531978 (CHEMBL4466342) Show SMILES CCCCc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(F)c(O)c1 Show InChI InChI=1S/C23H26FNO3/c1-2-3-4-16-5-7-17(8-6-16)22(27)18-11-13-25(14-12-18)23(28)19-9-10-20(24)21(26)15-19/h5-10,15,18,26H,2-4,11-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Displacement of [3H]CP55,940 to human CB2 receptor expressed in cell membranes after 90 mins by liquid scintillation counting				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483
					More data for this Ligand-Target Pair