BDBM50531979 CHEMBL4553078

SMILES: COc1ccc(F)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(cc1)C(C)C

InChI Key: InChIKey=KFUHPWSNJUSCIT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50531979   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50531979 (CHEMBL4553078) Show SMILES COc1ccc(F)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(cc1)C(C)C Show InChI InChI=1S/C23H26FNO3/c1-15(2)16-4-6-17(7-5-16)22(26)18-10-12-25(13-11-18)23(27)20-14-19(28-3)8-9-21(20)24/h4-9,14-15,18H,10-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MAGL using 4-NPA as substrate after 30 mins				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483
					More data for this Ligand-Target Pair