BDBM50531985 CHEMBL4463252

SMILES: Oc1cc(ccc1Br)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=ITHRRHVJXKNCGU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50531985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50531985 (CHEMBL4463252) Show SMILES Oc1cc(ccc1Br)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H17BrClNO3/c20-16-6-3-14(11-17(16)23)19(25)22-9-7-13(8-10-22)18(24)12-1-4-15(21)5-2-12/h1-6,11,13,23H,7-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	457	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MAGL using 4-NPA as substrate after 30 mins				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483
					More data for this Ligand-Target Pair