BDBM50531986 CHEMBL4442280

SMILES: Oc1cc(Cl)cc(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=NFMNBTDJGVWTTK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50531986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50531986 (CHEMBL4442280) Show SMILES Oc1cc(Cl)cc(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H17Cl2NO3/c20-15-3-1-12(2-4-15)18(24)13-5-7-22(8-6-13)19(25)14-9-16(21)11-17(23)10-14/h1-4,9-11,13,23H,5-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MAGL using 4-NPA as substrate after 30 mins				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483
					More data for this Ligand-Target Pair