BDBM50531992 CHEMBL4587797

SMILES: Oc1cccc(C(=O)N2CCC(CC2)C(=O)c2ccc(Cl)cc2)c1Br

InChI Key: InChIKey=ZHALVSFOXBQCRM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50531992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50531992 (CHEMBL4587797) Show SMILES Oc1cccc(C(=O)N2CCC(CC2)C(=O)c2ccc(Cl)cc2)c1Br Show InChI InChI=1S/C19H17BrClNO3/c20-17-15(2-1-3-16(17)23)19(25)22-10-8-13(9-11-22)18(24)12-4-6-14(21)7-5-12/h1-7,13,23H,8-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MAGL using 4-NPA as substrate after 30 mins				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483
					More data for this Ligand-Target Pair