BDBM50532000 CHEMBL4468106
SMILES: Oc1ccc(Br)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1
InChI Key: InChIKey=IOVXXWSLMSHSGM-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50532000![]() (CHEMBL4468106) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pisa Curated by ChEMBL | Assay Description Inhibition of human recombinant MAGL using 4-NPA as substrate after 30 mins | J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483 | |||||||||||
More data for this Ligand-Target Pair |