BDBM50532023 CHEMBL4454445
SMILES: Cc1cc(NC(=O)Cc2ccc(cc2)-c2ccccc2)n(n1)C1CCCCC1
InChI Key: InChIKey=BLTLZUGICACQHK-UHFFFAOYSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human)) | BDBM50532023 (CHEMBL4454445) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Activation of human GIRK1/4 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay | Bioorg Med Chem Lett 29: 791-796 (2019) Article DOI: 10.1016/j.bmcl.2019.01.027 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human)) | BDBM50532023 (CHEMBL4454445) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Activation of human GIRK1/2 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay | Bioorg Med Chem Lett 29: 791-796 (2019) Article DOI: 10.1016/j.bmcl.2019.01.027 | |||||||||||
More data for this Ligand-Target Pair |