BDBM50532049 CHEMBL4567000

SMILES: Cc1cc(NC(=O)Cn2nnc(n2)-c2ccccc2)n(n1)C1CCC(C)(C)CC1

InChI Key: InChIKey=CQPSNZJBDYRBQW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50532049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50532049 (CHEMBL4567000) Show SMILES Cc1cc(NC(=O)Cn2nnc(n2)-c2ccccc2)n(n1)C1CCC(C)(C)CC1 Show InChI InChI=1S/C21H27N7O/c1-15-13-18(28(24-15)17-9-11-21(2,3)12-10-17)22-19(29)14-27-25-20(23-26-27)16-7-5-4-6-8-16/h4-8,13,17H,9-12,14H2,1-3H3,(H,22,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>221	n/a	n/a	n/a	n/a
University of Nebraska Medical Center Curated by ChEMBL					Assay Description Activation of human GIRK1/2 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay				Bioorg Med Chem Lett 29: 791-796 (2019) Article DOI: 10.1016/j.bmcl.2019.01.027
					More data for this Ligand-Target Pair